Efficacy Guide

Efficacy Guide using Cisco Secure Email


This guide will lead you through administrating your Cisco Secure Email Gateway/Cloud Gateway for overall detection and efficacy hardening.

When we start talking about efficacy, we need to review the configuration and make sure that all services and features are appropriately configured and that those services and features are being utilized throughout the email pipeline (or the flow of email as it is processed by the email gateway).

Cisco does not recommend making drastic configuration changes to curb efficacy issues. Instead, validate a holistic configuration approach to finding where the problem may be.


No two customer configurations are the same. Each customer's self-efficacy is always different depending on message volume and message size and deployment size, and architecture.

Guide Checklist

This document will walk you through the following:

  • Introduction
  • Services Updates
  • Validate Detection Services
  • Review of Bypass, Accept or Allow Lists
  • Aggressive Profile for Anti-Spam
  • Review and Validate MX Records
  • Submissions to Talos
  • Support Requests
  • Security Review (Optional)


When reviewing and stepping through this guide, please complete the steps. Please do not skip a section, as this will decrease any chances of improving efficacy concerns.

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